Peptide GMP Manufacturing

BOC Sciences has more than 20 years of experience in the synthesis and cGMP production of peptides and peptide-related compounds. We specialize in production using liquid phase, solid phase and hybrid synthesis techniques. As one of the largest peptide contract manufacturers in the world, we have 4 production bases and nearly 1,000 employees.

The advanced technical team of BOC Sciences has accumulated rich professional knowledge in the field of peptides, and can develop more than 1,000 kinds of peptide compounds by combining SPPS, LPPS, structural chemistry and fragment polycondensation methods, with a success rate of over 98%. Our peptide production bases are equipped with advanced peptide synthesis, separation and purification and testing equipment to ensure a stable commercial production process and are an ideal business partner for your cGMP peptide needs.

What are Peptides?

Peptides are two or more amino acids connected by a peptide chain, between large molecule proteins and small molecule amino acids, and are functional nutrients essential for the body to accomplish various complex physiological activities. Peptides, as basic materials, constitute active substances in the body such as enzymes, hormones, antibodies, interneurons, etc., and regulate the physiological functions of various systems and cells, which are irreplaceable and important for cellular activity, functional activities, and the existence of life. Peptides can be categorized according to molecular weight size:

• Small peptides - Small peptides, also called small molecule peptides, are highly active peptides consisting of only 2 to 4 amino acids.
• Oligopeptides - Oligopeptides are peptides consisting of 2-10 amino acids, with molecular weights generally below 1000 daltons.
• Polypeptides - Polypeptides refer to peptides consisting of 10-50 amino acids.
• Proteins - Proteins generally refer to peptides consisting of more than 51 amino acids.

What is a Peptide Drug?

Peptide drugs mainly include peptide vaccines, anti-tumor peptides, anti-viral peptides, peptide-directed drugs, cytokine-mimicking peptides, antimicrobial active peptides, diagnostic peptides, as well as other small peptides for medicinal purposes. Because of their wide indications, high safety, and remarkable efficacy, peptide drugs can be widely used in the prevention, diagnosis, and treatment of tumors, cardiovascular and cerebrovascular diseases, hepatitis, diabetes, AIDS, and other diseases.

Advantages of Peptide Synthesis

• Cost-effective: We have established good cooperative relations with raw material suppliers, and can complete contract manufacturing at low cost on the premise of ensuring quality, saving your project expenses.
• Full product line: We support the manufacture of a range of simple to complex peptides, including linear peptides, macrocyclic peptides, modified peptides and complex peptide-based conjugates.
• Quality assurance: Our production lines meet current production quality management specifications and are operated by professional staff.

Capabilities of Peptide Manufacturing

Our broad portfolio of manufacturing equipment can meet the needs of every production stage.

Facilities

• 40,000 square feet of cGMP manufacturing space
• Class 100K clean rooms
• Milligram to kilogram cGMP production batches
• Production environment, health and safety management system

Equipment

• Solid phase and liquid phase reactors (20L-1000L)
• High performance liquid chromatography (HPLC)
• Freeze drying equipment
• microwave process equipment
• Multi-channel automation technology

Quality System

Our peptide production is strictly in accordance with F DA's cGMP guidelines, and an independent quality department has been set up to conduct a comprehensive review of the production process.

• Product testing
• Solubility testing
• Purity testing
• Molecular weight testing
• Impurity identification
• Microbial limit testing
• Client confidentiality, etc.
• Analysis verification and stability testing
• Process transfer method validation
• Central control and environmental control testing

Client Confidentiality

We are well aware of the importance of intellectual property rights and are committed to strictly guarding our clients' business secrets. The company has set up a security and confidentiality system to ensure the security of information in the process of cooperation. Everything is guided by your satisfaction. If you are interested in our peptide cGMP manufacturing service, please contact us immediately. In addition, custom development services for peptides can also be quickly obtained at BOC Sciences.